Profile

Professor Ewa M. Goldys holds a Personal Chair in the Department of Physics, Division of Information and Communication Sciences, Macquarie University.

Her expertise spans the fields of biophotonics, optical characterisation, ultrasensitive detection of analytes, biosensing, bioimaging. materials synthesis and characterisation and cathodoluminescence. The present projects belong at the interface of materials science, photonics and biotechnology and she is drawing on her earlier achievements in materials science and ultrasensitive optical characterisation where she made major contributions.

Her present projects belong to the cross-disciplinary area of Biophotonics. With the ARC support she has developed advanced methods of synthesis and characterisation of fluorescent nanoparticles for applications in fluorescence labelling. Her advanced expertise in ultrasensitive optical characterisation and nanotechnology leads to her novel approaches to biochemical and medical sensing and diagnostics, documented in numerous publications concerning self-organised growth and characterisation of nanostructures. Work in progress focuses on an innovative ultrasensitive surface plasmon resonance sensing system for the application in bioassays capable of sensing ultrasmall volumes, She demonstrated feasibility of the directional two-photon induced surface plasmon-coupled emission and demonstrated that surface plasmon sensing can be done using inexpensive plastic substrates. Her work concerned with metal nanoparticles led to the development of homogeneous silver-coated nanoparticles for their applications in fluorescence enhancement.

Her past most significant body of work focused on optical characterisation of trace impurities and defects in materials. She has made a breakthrough in the understanding of the role of oxygen impurity in GaN leading to establishment of commercially relevant methods of GaN growth at low temperatures and on inexpensive substrates. Similar advances were made in the understanding and control of hydrogen in GaN, demonstration of residual hydrogen and identification of elimination methods. She made contributions in the area of advanced microscopy with the development of cathodoluminescence as a diagnostic tool for quantitative analysis and applied to a wide variety of materials.

Her publication track record includes over 160 refereed journal publications and a similar number of conference publications, 9 book chapters. Her book "Fluorescence Applications in Biotechnology and Life Sciences" has been published by Wiley-Blackwell (2009). She is frequently invited to speak at international symposia and organised a number conferences as Chair, including "Biophotonics in Australia: Showcase and Strategic Planning", Macquarie University, Sydney, 22-25 February 2006, Light in Life Sciences Conference, Melbourne 24-27 November 2009 and as Committee Member, both locally and overseas.

Her funding record: comprises the total funding awarded of over $ 13 M, including over $ 4M as first applicant. Over 40 project awards included several industrial partnerships. The funding record also includes cross-disciplinary projects. She has established the Optical Characterisation Facility at Macquarie University with over $ 2M of LIEF funding.

She is Convenor of ARC/NHMRC Network "Fluorescence Applications in Biotechnology and Life Sciences", and former Deputy Director, Macquarie University Biotechnology Research Institute.She established the “Light in Life Sciences Foundation” designed to support research in the area of Fluorescence Applications in Biotechnology and Life Sciences.

Professor Goldys leads Nanobiophotonics research at Macquarie, bringing together research interests of 6 Research Associates and 7 PhD students who meet weekly at the Biofocus meetings. More information about postgraduate opportunities and projects is available at the website http://www.physics.mq.edu.au/~goldys/core

Selected publications

• "Fluorescence Applications in Biotechnology and Life Sciences" E.M. Goldys Editor, Wiley-Blackwell (2009) ISBN-10: 0470083700
• " Enhanced Flow Cytometry Based Bead Immunoassays by Using Metal Nanostructures", Wei Deng, Krystyna Drozdowicz-Tomsia, Dayong Jin and Ewa M Goldys, ANALYTICAL CHEMISTRY (Washington, DC, United States) (2009), 81(17), 7248-7255.
• "Formation of colloidal gold nanoparticles by using femtosecond laser ablation" , Sobhan, M. A.; Ams, M.; Withford, M. J.; Goldys, E. M, INTERNATIONAL JOURNAL OF NANOSCIENCE (2009), 8(1 & 2), 209-212.
• "Distinctive autofluorescence of urine samples from individuals with bacteriuria compared with normals", A. Anwer, S M Pernichery, S. Velmupad, EM Goldys, CLINICA CHIMICA ACTA 401 (2009) 73–75.
• "Quantitative characterization of different strains of Saccharomyces yeast by analysis of fluorescence microscopy images of cell populations", H. Bhatta, EM Goldys, JOURNAL OF MICROBIOLOGICAL METHODS (2009) 77, 77-84
• "A method to assess modifications of fluorophore radiative rate by plasmonic structures", Xie, Fang; Drozdowicz-Tomsia, Krystyna; Goldys, Ewa M. CHEMICAL PHYSICS LETTERS (2008), 466(4-6), 186-188.
• "Potential Use of Quantum Dots in Flow Cytometry", R Ibáñez-Peral, PL. Bergquist, MR. Walter, M Gibbs, EM. Goldys and Belinda Ferrari INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 9, 12, 2622-2638 (2008).
• "Linear absorption and molar extinction coefficient in direct semiconductor quantum dots" , Sun Jinjun, Ewa Goldys , JOURNAL OF PHYSICAL CHEMISTRY C (2008), 112(25), 9261-9266.
• "Enhanced Fluorescent Immunoassays on Silver Fractal-like Structures", Shtoyko, Tanya; Matveeva, Evgenia G.; Chang, I-Fen; Gryczynski, Zygmunt; Goldys, Ewa; Gryczynski, Ignacy. ANALYTICAL CHEMISTRY (Washington, DC, United States) (2008), 80(6), 1962-1966.
• "Enhanced Fluorescence Detection on Homogeneous Gold Colloid Self-Assembled Monolayer Substrates", Xie, Fang; Baker, Mark S.; Goldys, Ewa M. CHEMISTRY OF MATERIALS (2008), 20(5), 1788-1797.
• "Characterization of yeast strains by fluorescence lifetime imaging microscopy", Bhatta, Hemant; Goldys, Ewa M. FEMS YEAST RESEARCH (2008), 8(1), 81-87.
• "Coupled plasmon effects for the enhancement of fluorescent immunoassays", A.Barnett; EG Matveeva.; I Gryczynski, Z Gryczynski, E M. Goldys, PHYSICA B CONDENSED MATTER (Amsterdam, Netherlands) (2007), 394(2), 297-300.
• "Fluorescence Amplification by Electrochemically Deposited Silver Nanowires with Fractal Architecture", Goldys, Ewa M.; Drozdowicz-Tomsia, Krystyna; Xie, Fang; Shtoyko, Tanya; Matveeva, Eva; Gryczynski, Ignacy; Gryczynski, Zygmunt", JOURNAL OF THE AMERICAL CHEMICAL SOCIETY (2007), 129(40), 12117-12122.
• "Plasmon-enhanced fluorescence near metallic nanostructures: biochemical applications", Goldys, E. M.; Barnett, A.; Xie, F.; Drozdowicz-Tomsia, K.; Gryczynski, I.; Matveeva, E. G.; Gryczynski, Z.; Shtoyko, T. APPLIED PHYSICS A MATERIALS SCIENCE AND PROCESSING (2007), 89(2), 265-271.
• "Optical characterization of Eu-doped and undoped Gd2O3 nanoparticles synthesized by hydrogen flame pyrolysis method", K. Drozdowicz-Tomsia, EM Goldys., D. Dosev, I.M. Kennedy, S., Yatsunenko, M. Godlewski , JOURNAL OF THE AMERICAL CHEMICAL SOCIETY 128 (45) 114498-14505 (2006).
• "Use of fluorescence spectroscopy to differentiate yeast and bacterial cells", H. Bhatta, EM Goldys, R. Learmonth, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 71(1) 121 - 126, 2006
• "Fluorescence upconversion in Sm-doped Gd2O3", .Dosev, D.; Kennedy, I. M.; Godlewski, M.; Gryczynski, I.; Tomsia, K.; Goldys, E. M. APPLIED PHYSICS LETERS 88(1), 011906/1-011906/3, 2006
• "Growth-temperature-dependent cathodoluminescence properties of GaSb/GaAs quantum-dot multilayer structures" Drozdowicz-Tomsia, Krystyna; Goldys, Ewa M.; Motlan, Motlan; Zareie, Hadi; Phillips, Matthew R. APPLIED PHYSICS LETTERS 86(17), 173113/1-173113/3, 2005
• "Plastic Versus Glass Support for an Immunoassay on Metal-Coated Surfaces in Optically Dense Samples Utilizing Directional Surface Plasmon-Coupled Emission Evgenia G. Matveeva, Ignacy Gryczynski, Joanna Malicka, Zygmunt Gryczynski, Ewa Goldys, Joseph Howe, Klaus W. Berndt, and Joseph R. Lakowicz, JOURNAL OF FLUORESCENCE 15,(6), 865-71, Nov. 2005
• "Directional two-photon induced surface plasmon-coupled emission", Gryczynski, Ignacy; Malicka, Joanna; Lakowicz, Joseph R.; Goldys, Ewa M.; Calander, Nils; Gryczynski, Zygmunt. THIN SOLID FILMS 491(1-2), 173-176, 2005
• "Donor-acceptor pair emission enhancement in mass-transport-grown GaN" Paskova, T.; Arnaudov, B.; Paskov, P. P.; Goldys, E. M.; Hautakangas, S.; Saarinen, K.; Sodervall, U.; Monemar, B, JOURNAL OF APPLIED PHYSICS 98(3), 033508/1-033508/8, 2005
• "Doping-level-dependent optical properties of GaN: Mn", Gelhausen O, Malguth E, Phillips MR, Goldys EM, Strassburg M, Hoffmann A, Graf T, Gjukic M, Stutzmann M, APPLIED PHYSICS LETTERS 84 (22): 4514-4516, 2004
• "Dissociation of H-related defect complexes in Mg-doped GaN", Gelhausen O, Phillips MR, Goldys EM, Paskova T, Monemar B, Strassburg M, Hoffmann A, PHYSICAL REVIEW B 69 (12): Art. No. 125210, 2004
• "Propagating optical-phonon modes and their electron-phonon interactions in wurtzite GaN/AlxGa1-xN quantum wells", Shi JJ, Chu XL, Goldys EM, PHYSICAL REVIEW B 70 (11): Art. No. 115318, 2004
• "Influence of low-energy electron beam irradiation on defects in activated Mg-doped GaN", Gelhausen O, Klein HN, Phillips MR, Goldys EM"APPLIED PHYSICS LETTERS 81 (20): 3747-3749, 2002
• "Crystal size and oxygen segregation for polycrystalline GaN", Butcher KSA, Timmers H, Afifuddin, Chen PPT, Weijers TDM, Goldys EM, Tansley TL, Elliman RG, Freitas JA, JOURNAL OF APPLIED PHYSICS 92 (6): 3397-3403, 2002
• "Structural properties of a GaNxP1-x alloy: Raman studies" Buyanova IA, Chen WM, Goldys EM, Xin HP, Tu CW, APPLIED PHYSICS LETTERS 78 (25): 3959-3961, 2001
• "Elimination of nonuniformities in thick GaN films using metalorganic chemical vapor deposited GaN templates", Valcheva E, Paskova T, Abrashev MV, Paskov PP, Persson POA, Goldys EM, Beccard R, Heuken M, Monemar B, JOURNAL OF APPLIED PHYSICS 90 (12): 6011-6016, 2001
• "Modeling of the free-electron recombination band in emission spectra of highly conducting n-GaN", Arnaudov B, Paskova T, Goldys EM, Evtimova S, Monemar B, PHYSICAL REVIEW B 64 (4): Art. No. 045213, 2001
• "Influence of growth rate on the structure of thick GaN layers grown by HVPE", Paskova T, Goldys EM, Yakimova R, Svedberg EB, Henry A, Monemar B, JOURNAL OF CRYSTAL GROWTH 208 (1-4), 2000
• "Cathodoluminescence depth-profiling studies of GaN/AlGaN quantum-well structures", Godlewski M, Goldys EM, Phillips MR, Langer R, Barski A, JOURNAL OF MATERIALS RESEARCH 15 (2): 495-501, 2000
• "Spectroscopic properties of thulium-doped crystalline materials including a novel host, La2Be2O5: a comparative study", Sudesh V, Goldys EM, JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS 17 (6): 1068-1076, 2000
• "Signatures of excitonic dark states in time-resolved coherent response of a microcavity", E.M. Goldys, G.C. La Rocca, F. Bassani, PHYSICAL REVIEW B 61, 10 346 - 10 360, (2000).
• "Optical-phonon modes and electron-phonon interaction in arbitrary semiconductor planar microcavities ", Shi JJ, Sanders BC, Pan SH, Goldys EM, PHYSICAL REVIEW B 60 (23): 16031-16038, 1999
• "Shear piezoelectric coefficients of gallium nitride and aluminum nitride ", Muensit S, Goldys EM, Guy IL, APPLIED PHYSICS LETTERS 75 (25): 3965-3967, 1999
• "Extensional piezoelectric coefficients of gallium nitride and aluminum nitride", Guy IL, Muensit S, Goldys EM, APPLIED PHYSICS LETTERS 75 (26): 4133-4135, 1999
• "Contribution of free-electron recombination to the luminescence spectra of thick GaN films grown by hydride vapor phase epitaxy", Arnaudov B, Paskova T, Goldys EM, Yakimova R, Evtimova S, Ivanov IG, Henry A, Monemar B, JOURNAL OF APPLIED PHYSICS 85 (11): 7888-7892, 1999
• "Microstructural evolution of GaSb self-assembled islands grown by metalorganic chemical vapor deposition", Kinder BM, Goldys EM, APPLIED PHYSICS LETTERS 73 (9): 1233-1235, 1998
• "Low temperature growth of gallium nitride on quartz and sapphire substrates", E.M. Goldys, M.J. Paterson, H.Y. Zuo, T.L. Tansley, MATERIALS SCIENCE FORUM vol. 264-268 pt 2 p. 1205-8 (1998).
• "Direct observation of large-scale nonuniformities in hydride vapor-phase epitaxy-grown gallium nitride by cathodoluminescence", Goldys EM, Paskova T, Ivanov IG, Arnaudov B, Monemar B, APPLIED PHYSICS LETTERS 73 (24): 3583-3585, 1998
• "Influence of the surface morphology on the yellow and "edge" emissions in wurtzite GaN", Godlewski M, Goldys EM, Phillips MR, Langer R, Barski A, APPLIED PHYSICS LETTERS 73 (25): 3686-3688, 1998